Speaker
Description
Steroidal hormones play a crucial role as chemical messengers within organisms. Their profound influence on various physiological processes makes them a prime focus for analysis in healthcare and many other biochemical fields. While their metabolic pathways are extensively studied and numerous MS(/MSn) spectra are available (e.g., in the HMDB), the fragmentation pathways of steroidal hormones and their derivatives in tandem mass spectrometry are yet to be completely understood. The complex fragmentation mechanisms of steroids pose significant challenges in interpreting MSn spectra and elucidating fragment structures. This work aims to characterize MS/MS fragments using infrared ion spectroscopy (IRIS) and propose potential candidate structures.
